HOW DOES THE WAY IN WHICH INDIVIDUAL STUDENTS BEHAVE AFFECT THE SHARED CONSTRUCTION OF MEANING?

Audio taped discussions between three students have been examined to shed light on the way in which the behaviour of individual students may affect the shared construction of meaning with graphical calculators. These discussions revealed a complex pattern of interaction between the students. Each student was responsible for defining his or her own role within the discourse and these roles appeared to change as the discussion progressed. With reference to the framework offered by Winbourne and Watson (1998), it is proposed that local communities of practice have been established and that the individual student's positioning within the community of practice determines their success as a learner and contributes towards the creation of shared knowledge.     

ORGANOPHOSPHORUS COMPOUNDS AS POTENTIAL FUNGICIDES. PART I. N-(ω-GUANI-DINOALKYL)AMINOALKANEPHOSPHONIC ACIDS AND THEIR AMINOPHOSPHONIC PRECURSORS: PREPARATION,NMR SPECTROSCOPY,AND FAST ATOM BOMBARDMENT MASS SPECTROMETRY

Abstract

N-(ω-Aminoalkyl)- and N-(ω-guanidinoalkyl)-aminoalkanephosphonic acids have been prepared from α, ω-diaminoalkanes by reaction with chloromethanephosphonic acid (or an ester of a halogeno-alkanephosphonic acid), followed by treatment with S-methylisothiouronium chloride. Ethylene diamine yielded 1-phosphonomethyl-2-iminoimidazolidine. A number of 1:1 salts of the α, ω-diamines and chloromethanephosphonic acid are also reported. Doubly charged zwitterionic structures are assigned to both ω-amino and ω-guanidino compounds on the basis of ³¹P and ¹³C nmr data. Thus the addition of an excess of acid (D₂SO₄) causes the ³¹P chemical shift to move to higher field, from ca. 8 to 14 ppm, whilst ¹ Jpc increases from ca. 130 to 150 Hz. The ¹H and ¹³C chemical shifts of the terminal methylene groups in the polymethylene chain are unaffected by acidification.

Fast atom bombardment mass spectrometry gives rise to characteristic [M + H]⁺ ions, frequently as the base peak, and to fragmentations involving the loss of phosphorous acid, or the formation of ions resulting from carbon-nitrogen or carbon-carbon cleavage. The compounds show activity against a number of fungal pathogens and other microbial organisms.     

Products in the Reactions of Trialkyl Phosphites with α-Halogeno-acetophenones in Alcoholic Media

Abstract

α-Hydroxyphosphonates are formed, in addition to vinyl phosphates and dehalogenated ketones, in the reactions of trimethyl phosphite (in methanol) or triethyl phosphite (in ethanol) with variously substituted α-chloro, α-bromo, and α,α,-dichloro-acetophenones. Tri-isopropyl phosphite in propan-2-ol gives only the vinyl phosphate. Ketophosphonates are not detectable amongst the reaction products under the conditions used. Trends in product composition can be correlated with the leaving ability of halogen, substituent effects, structure of the phosphite, and reaction temperature. Reactant ratios may also influence the product composition. The reactions of trimethyl phosphite in methanol with 4-nitro-α-chloroacetophenone, or α,α-dichloroacetophenones yield the dehalogenated α-hydrogxyphosphonates in addition. In the case of the 4-nitro derivative, this product cannot be accounted for by reaction of the phosphite with dehalogenated ketone (4-nitroacetophenone). Dehalogenation of the first-formed α-hydroxyphosphonate was, however, shown to occur under reaction conditions and appears to require the removal of positive chlorine, followed by protonation. Reactions of the α,α-dichloroacetophenones were similar to those of the α-chloroacetophenones, giving the corresponding chlorovinyl phosphate, α,α-dichloro-α-hydroxyphosphonate, and monodehalogenated ketone(i.e. α-chloroacetophenone); the latter was not however detected as it reacted further with excess phosphite to give the expected products as described above. Possible mechanisms for the various reactions are discussed. The ¹H and ¹³C nmr spectra of the α-hydroxy-phosphonates show magnetic non-equivalence of the two alkoxy groups, attributed to restricted rotation about the P-C bond as a result of intramolecular hydrogen-bonding.     

THE PREPARATION OF TRIALKYL PHOSPHITES DIRECTLY FROM THE ELEMENT

Abstract

The reaction between finely divided white phosphorus and several alkoxide ions in the presence of tetrachloromethane and excess of alcohol has been investigated under a variety of conditions. High yields of trialkylphosphite are obtained when two equivalents of alkoxide are used. With one equivalent of alkoxide, dialkylphosphonate is formed in comparable yield. Maximum yields of triester are obtained within 1–3 h at room temperature. Prolonged treatment results in the conversion of trialkylphosphite to phosphate by reaction with tetrachloromethane. Phenolate ions are unreactive under the same experimental conditions. The mechanism of the reaction is discussed.     

1-AMINO-1-ARYL- AND 1-AMINO-1-HETEROARYL-METHANEPHOSPHONIC ACIDS AND THEIR N-BENZHYDRYL–PROTECTED DIETHYL ESTERS: PREPARATION AND CHARACTERIZATION

n-Benzhydryl-protected diethyl[3.3pc] esters of 1-amino-1-aryl- (phenyl, cumyl, p-dimethylaminophenyl, piperonyl, 1′-naphthyl, 9′-anthryl, 1′-pyrenyl) and 1-amino-1-heteroaryl- (furyl, 2′-thienyl, 3′-thienyl, 2′-pyrrolyl)-methanephosphonic acids, prepared by the addition of diethyl phosphite to the corresponding benzhydryl imines, have been isolated, purified, and characterized. The presence of chiral α -carbon and prochiral phosphorus in these esters gives rise to complicated features in their NMR spectra, which are discussed. Hydrolysis of the crude 1-aryl compounds in situ gave modest yields of the corresponding aminophosphonic acids (except for 1′-pyrenyl). Of the 1-heteroaryl derivatives, only the 2′-thienyl compound gave the expected aminophosphonic acid; in other cases, alternative[-18pc] modes of decomposition may occur under hydrolytic conditions. NMR and mass spectral data are given for all products.     

Multicore, tapered optical fiber for nonlinear pulse reshaping and saturable absorption

We present a new method to create a coupled waveguide array via tapering a seven-core telecommunications fiber. The fiber based waveguide array is demonstrated to exhibit the novel physics associated with coupled waveguide arrays, such as discrete diffraction and discrete self-focusing. The saturable absorber characteristics of the device are characterized and an autocorrelation measurement reveals significant single-pass pulse reshaping.     

Sigmoids as precursors of solar eruptions

Coronal mass ejections (CMEs) appear to originate preferentially in regions of the Sun's corona that are sigmoidal, i.e., have sinuous S or reverse-S shapes. Yohkoh solar X-ray images have been studied before and after a modest number of Earth-directed (halo) CMEs. These images tend to show sigmoidal shapes before the eruptions and arcades, cusps, and transient coronal holes after. Using such structures as proxies, it has been shown that there is a relationship between sigmoidal shape and tendency to erupt. Regions in the Sun's corona appear sigmoidal because their magnetic fields are twisted. Some of this twist may originate deep inside the Sun. However, it is significantly modulated by the Coriolis force and turbulent convection as this flux buoys up through the Sun's convection zone. As the result of these phenomena, and perhaps subsequent magnetic reconnection, magnetic flux ropes form. These flux ropes manifest themselves as sigmoids in the corona. Although there are fundamental reasons to expect such flux ropes to be unstable, the physics is not as simple as might first appear, and there exist various explanations for instability. Many gaps need to be filled in before the relationship between sigmoids and CMEs is well enough understood to be a useful predictive tool     

Phosphorbestimmungsmethoden

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